Panagiotis Papageorgis
Dean, Professor, Biological Sciences
22713158
School of Sciences
Dean's Office
Qualification | Year | Awarding Institution | Department | Thesis title |
PhD | 2009 | Boston University School of Medicine | Cell and Molecular Biology/ Genetics and Genomics | The role of Smad signaling in cancer progression |
BSc | 2003 | National and Kapodistrian University of Athens | Biology | Purification and biochemical characterization of an endogenous inhibitor of L-Dopa decarboxylase |
Period of employment | Employer | Location | Position | |
From | To | |||
2014 | date | European University Cyprus | Nicosia, Cyprus | Associate Professor |
2010 | 2014 | University of Cyprus | Nicosia, Cyprus | Post-doctoral fellow |
2009 | 2010 | Boston University School of Medicine | Boston, USA | Post-doctoral fellow |
Year | Title | Other authors | Journal and Publisher / Conference | Vol. | Pages |
2021 | Histone N-terminal acetyltransferase NAA40 links one-carbon metabolism to chemoresistance | Demetriadou, A. Raoukka, E. Charidemou, C. Mylonas, C. Michael, S. Parekh, C. Koufaris, P. Skourides, P. Tessarz and A. Kirmizis | Oncogene | Doi: 10.1038/s41388-021-02113-9 | |
2021 | Apoptosis deregulation and the development of multi-drug resistance | C.M. Neophytou, I. Trougakos and N. Erin | Cancers | 13 | https://doi.org/10.3390/cancers13174363 |
2021 |
The role of tumor microenvironment in cancer metastasis: Molecular mechanisms and therapeutic opportunities |
C.M. Neophytou, M. Panagi, T. Stylianopoulos | Cancers | 13 | https://doi.org/10.3390/cancers13092053 |
2020 | Normalizing the microenvironment overcomes vessel compression and resistance to nano-immunotherapy in breast cancer lung metastasis | F. Mpekris, M. Panagi, C. Voutouri, J. Martin, R. Samuel, S. Takahashi, N. Gotohda, T. Suzuki, P. Demetriou, C. Pierides, L. Koumas, P. Costeas, M. Kojima, G. Ishii, A. Constantinidou, K. Kataoka, H. Cabral, T. Stylianopoulos | Advanced Science | 8 | https://doi.org/10.1002/advs.202001917 |
2019 | Activin A Signaling Regulates IL13Rα2 Expression to Promote Breast Cancer Metastasis | Kalli M, Mpekris F, Wong CK, Panagi M, Ozturk S, Thiagalingam S, Stylianopoulos T. | Frontiers in Oncology | 9 | doi: 10.3389/fonc.2019.00032 |
2018 | Molecular mechanisms and emerging therapeutic targets for triple-negative breast cancer metastasis | C.N. Neophytou, P. Boutsikos | Frontiers in Oncology | 8 | https://doi.org/10.3389/fonc.2018.00031 |
2017 | Tranilast-induced stress alleviation in solid tumors improves the efficacy of chemo- and nanotherapeutics in a size-independent manner | C. Polydorou, F. Mpekris, C. Voutouri, E. Agathokleous, C. Kapnissi-Christodoulou, T. Stylianopoulos | Scientific Reports | 7 | doi: 10.1038/srep46140 |
2015 | Targeting IL13RA2 activates STAT6-p63 pathway to suppress breast cancer lung metastasis. | Ozturk S., Lambert A.W., Tzatsos A., Neophytou C.M., Wong C.K., Thiagalingam S. Constantinou AI. | Breast Cancer Research | 17 | doi: 10.1186/s13058-015-0607-y |
2011 | Smad4 inactivation promotes malignancy and drug resistance of colon cancer. | Cheng K.H., Ozturk S., Gong Y., Lambert AW., Abdolmaleky H.M., Zhou JR., Thiagalingam S. | Cancer Research | 71 | 998-1008 |
2010 | Smad signaling is required to maintain epigenetic gene silencing during breast cancer progression | Lambert A.W., Ozturk S., Gao F., Pan H., Manne U., Alekseyev Y., Thiagalingam A., Abdolmaleky H., Lenburg M.,Thiagalingam S. | Cancer Research | 70 | 968-978 |
Date | Topic | International / Local | Location* | Role in Exhibition |
2021 | Unveiling the transcriptional landscape that regulates colonization of dormant metastatic breast cancer cells to the lungs | International | Nicosia, Cyprus | Talk |
2020 | Remodelling the tumor microenvironment to improve the efficacy of immunotherapy | International | Athens, Greece | Invited talk |
2019 | Remodelling the tumor microenvironment to improve the efficacy of cancer therapy. | International | Nicosia, Cyprus | Invited talk |
2018 | Remodelling the tumor microenvironment to improve efficacy of chemo- and nanotherapeutics in solid tumors | International | Lausanne, Switzerland | Poster presentation |
2017 | IL13Rα2: a target for controlling breast cancer metastasis to the lungs. | Local | Limassol, Cyprus | Invited talk |
2017 | Designing strategies to target IL13Ra2-mediated breast cancer metastasis. | International | Athens, Greece | Invited talk |
2017 | Tranilast-induced stress alleviation in solid tumors improves the efficacy of chemo- and nanotherapeutics in a size independent manner. | International | Basel, Switzerland | Poster presentation |
2016 | Deciphering the molecular complexity of cancer metastasis. | International | Athens, Greece | Invited talk |
2016 | Molecular mechanisms of cancer metastasis | Local | Larnaca, Cyprus | Invited talk |
2015 | Targeting IL13Ralpha2 activates STAT6-TP63 pathway to suppress breast cancer metastasis. | International | Athens, Greece | Invited talk |
Date | Title | Funded by | Project Role* |
03/2021 - 02/2023 | Targeting the desmoplastic tumor microenvironment to improve the efficacy of pancreatic cancer immunotherapy | Research and Innovation Foundation (EXCELLENCE 0421/0179) Allocated funding: 174,533.25 € | Project coordinator |
03/2021 - 02/2023 | Investigating the mechanistic and therapeutic link between glucose and Histone acetyltransferase 1 (HAT1) activity in the aggressiveness of Glioblastoma multiforme (GBM) | Research and Innovation Foundation (EXCELLENCE 0421/0342) Allocated funding: 74,749.60 € | Project Partner |
03/2021 - 02/2023 | Deciphering the molecular and biological function of histone H2A.X N-terminal acetylation | Research and Innovation Foundation (EXCELLENCE 0421/0152) Allocated funding: 74.449,00 € | Project Partner |
01/2019 - 12/2021 | Unveiling novel molecular mechanisms that regulate colonization of dormant metastatic breast cancer cells. | Research and Innovation Foundation (POST-DOC 0916/0044) Allocated funding: 159.992 € | Project Partner |
09/2019 - 08/2021 | Optimizing immunotherapy in triple-negative breast cancer by normalizing the tumor microenvironment | Research and Innovation Foundation (POST-DOC 0718/0084) Allocated funding: 15.600 € | Project Partner |
09/2019 - 08/2021 | Function of the histone N-terminal acetyltransferase Naa40 in liver-metabolic reprogramming and oncogenesis | Research and Innovation Foundation (EXCELLENCE 0918/0081) Allocated funding: 15.000 € | Project Partner |
01/2019 - 12/2022 | Center for Preclinical evaluation and optimization of cancer nanomedicine | Research and Innovation Foundation (INFRASTRUCTURES 1216/0052) Allocated funding: 39,552 € | Project Partner |
01/2019 - 12/2021 | Functional and therapeutic implications of histone N-terminal acetyltransferase Naa40 in colorectal oncogenesis | Research and Innovation Foundation (EXCELLENCE 1216/0036) Allocated funding: 34,488 € | Project Partner |
06/2016 - 05/2018 | Elucidation of the signaling mechanisms that promote IL13Rα2-mediated breast cancer metastasis | Research and Innovation Foundation (KOULTOURA 0415/03) Χρηματοδότηση: 35.000 € | Project coordinator |
09/2010 - 12/2013 | Identification and functional characterization of novel genes involved in breast cancer metastasis | Research and Innovation Foundation (DIDAKTOR 0609/24) Allocated funding: 150.000 € | Project coordinator |
Period | Organization | Title of Position or Service | Key Activities |
09/2018 – to date | European University Cyprus | Dean, School of Sciences | Academic and Administrative leader of the School of Sciences, responsible for the academic operations, general welfare and the development of the School. |
2021-2027 | Program Committee - Horizon Europe | National Representative of the “Health” Configuration of Horizon Europe Program Committee | Promotion of national positions in the formulation of Horizon Europe Call programs in the "Health" Configuration. |
2021-2024 | National Committee for the Protection of Animals for Scientific Purposes | Member of the National Committee for the Protection of Animals for Scientific Purposes | Evaluation and licensing of work permit applications and personal permits for the use of animals for scientific purposes |
2021 | National Science Center, Poland | Grant proposal reviewer | Review of grant proposals |
2019-to date | European University Cyprus | Coordinator of the MSc Cancer Biology Program | Responsible all academic operations and matters pertaining the MSc Cancer Biology program. |
Date | Title | Awarded by: |
2015 | Young Researcher Award | Research Promotion Foundation Cyprus |
2007 | First prize for the Henry I. Russek Student Achievement Award | Boston University School of Medicine |
2006 | Second prize for the Henry I. Russek Student Achievement Award | Boston University School of Medicine |
2006 | Honourable mention for the Evans Research Day | Boston University School of Medicine |
2005 | First prize for the “Outstanding poster award competition” | Boston University School of Medicine, Department of Genetics and Genomics |
Date | Title | Key Activities: |
2006 – to date | 42 articles in international peer-reviewed journals and 4 book chapters | Author/Researcher |
2006 – to date | Citations: 2672; h-index: 22; i10-index: 32 (source Google Scholar, as of 23/11/21) https://scholar.google.com/citations?user=10jCj7kAAAAJ&hl=en | Author/Researcher |
2010 - to date | Reviewer | Manuscript reviews for several peer-reviewed journals |
2018 | Scientific committee member | Member of the Scientific committee for the 7th International Conference of the Cyprus Society of Human Genetics |
2018 | Scientific committee member | Member of the Scientific committee for the 6th Multithreaded Biomedical Congress |
2017 | Founding member of Pancyprian Association for Cystic Fibrosis | Founding member |
2016 | Ad hoc evaluations | Member of the several PhD Examination Committee at the University of Cyprus, the Cyprus Institute of Neurology and Genetics and National and Kapodistrian University |
July 2016-July 2017 | EUC Faculty Development | Completion of the EUC Faculty Development Program |
2016 | Invited lecturer | Invited lecture “Deciphering the molecular complexity of cancer metastasis”. 12th Educational Biology Conference OELMEK, Nicosia, Cyprus |
2012 | Invited lecturer | Invited lecture “Integrating transcriptomic and genetic approaches to identify novel mediators of breast cancer metastasis”. Progress in combination therapy of cancer using novel immunomodulators, “Inspire” Conference, Athens, Greece |